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PERSPECTIVES
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1-18
| Cyclin-Dependent Kinase Inhibitors: Useful Targets in Cell Cycle Regulation
Thais M. Sielecki,
John F. Boylan,
Pamela A. Benfield, and
George L. Trainor
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COMMUNICATIONS
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19-21
Selective Plasma Hydrolysis of Glucocorticoid  -Lactones and Cyclic Carbonates by the Enzyme Paraoxonase: An Ideal Plasma Inactivation Mechanism
Keith Biggadike,
Richard M. Angell,
Colin M. Burgess,
Rosanne M. Farrell,
Ashley P. Hancock,
Andy J. Harker,
Wendy R. Irving,
Chris Ioannou,
Panayiotis A. Procopiou,
Rupert E. Shaw,
Yemisi E. Solanke,
Onkar M. P. Singh,
Michael A. Snowden,
Rob J. Stubbs,
Sarah Walton, and
Helen E. Weston
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22-26
Discovery of Orally Active Nonpeptide Vitronectin Receptor Antagonists Based on a 2-Benzazepine Gly-Asp Mimetic
William H. Miller,
Doreen P. Alberts,
Pradip K. Bhatnagar,
William E. Bondinell,
James F. Callahan,
Raul R. Calvo,
Russell D. Cousins,
Karl F. Erhard,
Dirk A. Heerding,
Richard M. Keenan,
Chet Kwon,
Peter J. Manley,
Kenneth A. Newlander,
Stephen T. Ross,
James M. Samanen,
Irene N. Uzinskas,
Joseph W. Venslavsky,
Catherine C.-K. Yuan,
R. Curtis Haltiwanger,
Maxine Gowen,
Shing-Mei Hwang,
Ian E. James,
Michael W. Lark,
David J. Rieman,
George B. Stroup,
Leonard M. Azzarano,
Kevin L. Salyers,
Brian R. Smith,
Keith W. Ward,
Kyung O. Johanson, and
William F. Huffman
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ARTICLES
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27-40
Isoxazolines as Potent Antagonists of the Integrin  v 3
William J. Pitts,
John Wityak,
Joanne M. Smallheer,
A. Ewa Tobin,
James W. Jetter,
Jennifer S. Buynitsky,
Patricia P. Harlow,
Kimberly A. Solomon,
Martha H. Corjay,
Shaker A. Mousa,
Ruth R. Wexler, and
Prabhakar K. Jadhav
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41-58
Disubstituted Indazoles as Potent Antagonists of the Integrin v3
Douglas G. Batt,
Joseph J. Petraitis,
Gregory C. Houghton,
Dilip P. Modi,
Gary A. Cain,
Martha H. Corjay,
Shaker A. Mousa,
Peter J. Bouchard,
Mark S. Forsythe,
Patricia P. Harlow,
Frank A. Barbera,
Susan M. Spitz,
Ruth R. Wexler, and
Prabhakar K. Jadhav
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59-70
QSAR Analysis of  8-THC Analogues: Relationship of Side-Chain Conformation to Cannabinoid Receptor Affinity and Pharmacological Potency
Alison R. Keimowitz,
Billy R. Martin,
Raj K. Razdan,
Peter J. Crocker,
S. Wayne Mascarella, and
Brian F. Thomas
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71-95
Pharmacophore/Receptor Models for GABAA/BzR Subtypes (132, 532, and 632) via a Comprehensive Ligand-Mapping Approach
Qi Huang,
Xiaohui He,
Chunrong Ma,
Ruiyan Liu,
Shu Yu,
Charlotte A. Dayer,
Galen R. Wenger,
Ruth McKernan, and
James M. Cook
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96-102
3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-ones: Tricyclic Heteroaromatic Derivatives as a New Class of Benzodiazepine Receptor Ligands
Giampaolo Primofiore,
Federico Da Settimo,
Sabrina Taliani,
Anna Maria Marini,
Concettina La Motta,
Ettore Novellino,
Giovanni Greco,
Marco Gesi,
Letizia Trincavelli, and
Claudia Martini
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103-113
Structure-Property Model for Membrane Partitioning of Oligopeptides
Lene Hjorth Alifrangis,
Inge T. Christensen,
Anders Berglund,
Maria Sandberg,
Lars Hovgaard, and
Sven Frokjaer
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114-122
Synthesis and Opioid Receptor Affinity of Morphinan and Benzomorphan Derivatives: Mixed  Agonists and  Agonists/Antagonists as Potential Pharmacotherapeutics for Cocaine Dependence
John L. Neumeyer,
Jean M. Bidlack,
Rushi Zong,
Venkatesalu Bakthavachalam,
Peng Gao,
Dana J. Cohen,
S. Stevens Negus, and
Nancy K. Mello
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123-127
Synthesis and SAR of 4-Aryl-2-hydroxy-4-oxobut-2-enoic Acids and Esters and 2-Amino-4-aryl-4-oxobut-2-enoic Acids and Esters: Potent Inhibitors of Kynurenine-3-hydroxylase as Potential Neuroprotective Agents
Martin J. Drysdale,
S. Lucy Hind,
Marilyn Jansen, and
John F. Reinhard, Jr.
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BRIEF ARTICLES
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128-132
A Light-Inactivated Antibiotic
Wenlin Lee,
Zhi-Hong Li,
Sergei Vakulenko, and
Shahriar Mobashery
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133-138
Binding Mode of the 4-Anilinoquinazoline Class of Protein Kinase Inhibitor: X-ray Crystallographic Studies of 4-Anilinoquinazolines Bound to Cyclin-Dependent Kinase 2 and p38 Kinase
Lisa Shewchuk,
Anne Hassell,
Bruce Wisely,
Warren Rocque,
William Holmes,
James Veal, and
Lee F. Kuyper
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